Atletico San Luis vs Santos Laguna: Prediction, Betting Tips & Match Preview – 22 April

Atletico San Luis

L W W L L

15th place in Clausura

2-0

22/04/2026 21:00

Santos Laguna

L W D W L

11th place in Clausura

Primera Division de Mexico

MATCH INTRO

Betiball's prediction for Atletico San Luis vs Santos Laguna on 22 April 2026 (kick-off: 21:00) is built from both teams' recent form, head-to-head history, squad availability, and tactical analysis. Read the full Atletico San Luis vs Santos Laguna preview before placing your bet.

Atletico San Luis will face Santos Laguna in Primera Division de Mexico on April 22, 2026 at 21:00.
Atletico San Luis are currently 15th with 16 points after 17 matches.
Santos Laguna sit 11th with 20 points from 17 matches.
Current model prediction leans green with a projected score of 2 - 1 and average coefficient 1.67.

Predictions 1x2 Under/Over 2.5 1X2 Live Half Time Half Time / Full Time Both To Score Double chance Handicap Scorers Corners Cards

Home team Away team

Probability %

Pred

Correct

Avg.g

Coef.

Score.

Live coef.

Weather

21:00

2026-04-22

Atletico San Luis vs Santos Laguna - Prediction & Odds

Atletico San Luis

Santos Laguna

2026-04-22 21:00

STANDINGS UP TO 22/04/2026

Clausura	PTS	GP	W	D	L	GF	GA	+/-

01 Toluca	37	17	11	4	2	43	18	25
02 Tigres UANL	36	17	10	6	1	35	16	19
03 CDSyC Cruz Azul	35	17	10	5	2	32	20	12
04 Club America	34	17	10	4	3	33	18	15
05 Monterrey	31	17	9	4	4	33	29	4
06 Chivas Guadalajara	29	17	9	2	6	29	22	7
07 Club Tijuana	24	17	6	6	5	29	23	6
08 FC Juarez	23	17	6	5	6	27	28	-1
09 Pachuca	22	17	6	4	7	21	21	0
10 Pumas U.N.A.M.	21	17	5	6	6	24	25	-1
11 Santos Laguna	20	17	6	2	9	22	28	-6
12 Queretaro FC	20	17	6	2	9	19	29	-10
13 Necaxa	17	17	4	5	8	24	32	-8
14 Atlas	17	17	4	5	8	24	35	-11
15 Atletico San Luis	16	17	5	1	11	25	29	-4
16 Mazatlan FC	14	17	2	8	7	20	29	-9
17 Club Leon	13	17	3	4	10	14	31	-17
18 Puebla	12	17	3	3	11	21	42	-21

Apertura	PTS	GP	W	D	L	GF	GA	+/-

01 Pumas U.N.A.M.	36	17	10	6	1	34	17	17
02 Chivas Guadalajara	36	17	11	3	3	33	17	16
03 CDSyC Cruz Azul	33	17	9	6	2	31	18	13
04 Pachuca	31	17	9	4	4	25	19	6
05 Toluca	30	17	8	6	3	28	16	12
06 Atlas	26	17	7	5	5	16	18	-2
07 Tigres UANL	25	17	7	4	6	28	18	10
08 Club America	25	17	7	4	6	20	17	3
09 Club Tijuana	23	17	5	8	4	19	17	2
10 Club Leon	22	17	7	1	9	22	32	-10
11 Queretaro FC	20	17	4	8	5	17	21	-4
12 FC Juarez	19	17	5	4	8	26	32	-6
13 Monterrey	18	17	5	3	9	22	24	-2
14 Atletico San Luis	18	17	5	3	9	24	27	-3
15 Necaxa	18	17	5	3	9	19	25	-6
16 Mazatlan FC	15	17	4	3	10	22	37	-15
17 Puebla	13	17	3	4	10	13	26	-13
18 Santos Laguna	12	17	3	3	11	20	38	-18

Head To Head

21/09/2025 19:00

Santos Laguna

1 - 4

Atletico San Luis

MEX D1

30/03/2025 19:00

Santos Laguna

2 - 3

Atletico San Luis

MEX D1

28/09/2024 23:10

Atletico San Luis

3 - 1

Santos Laguna

MEX D1

28/04/2024 20:00

Santos Laguna

0 - 3

Atletico San Luis

MEX D1

11/11/2023 19:00

Atletico San Luis

0 - 2

Santos Laguna

MEX D1

18/02/2023 19:00

Atletico San Luis

1 - 1

Santos Laguna

MEX D1

Santos Laguna

17%

Draw

17%

Atletico San Luis

67%

Atletico San Luis Last 6 matches

17/04/2026 21:00

Atletico San Luis 0 - 2 Pumas U.N.A.M.

MEX D1

12/04/2026 21:00

Toluca 1 - 1 Atletico San Luis

MEX D1

04/04/2026 19:00

Monterrey 1 - 2 Atletico San Luis

MEX D1

21/03/2026 21:00

Atletico San Luis 1 - 2 Club Leon

MEX D1

14/03/2026 19:00

Atletico San Luis 1 - 1 Pachuca

MEX D1

07/03/2026 19:00

CDSyC Cruz Azul 3 - 0 Atletico San Luis

MEX D1

Win

17%

Draw

33%

Lost

50%

Last 6 matches Santos Laguna

19/04/2026 19:00

Santos Laguna 0 - 1 Atlas

MEX D1

11/04/2026 21:00

Pachuca 4 - 2 Santos Laguna

MEX D1

04/04/2026 23:10

Santos Laguna 1 - 1 Club America

MEX D1

22/03/2026 19:00

Santos Laguna 2 - 1 Puebla

MEX D1

14/03/2026 19:05

Chivas Guadalajara 3 - 0 Santos Laguna

MEX D1

08/03/2026 23:05

Club Tijuana 1 - 2 Santos Laguna

MEX D1

Win

33%

Draw

17%

Lost

50%

Overall Home/Away

Full time First half Second half

All leagues Primera Division de Me...

Played games

Atletico San Luis

Santos Laguna

Goals

Scored

Avg. per game

1.35

Conceded

Avg. per game

1.53

Scored

Avg. per game

1.47

Conceded

Avg. per game

1.29

Scored a goal

In last 6 home matches

YesNo

4 (67%)2 (33%)

In last 6 home matches

NoYes

5 (83%)1 (17%)

In last 17 home matches

YesNo

13 (76%)4 (24%)

In last 17 home matches

NoYes

15 (88%)2 (12%)

Atletico San Luis

Recent matches

Santos Laguna

Under /Over

(82%)14 3(18%)

1.5

Full Time

Under /Over

(71%)12 5(29%)

Under /Over

(24%)4 13(76%)

1.5

1st Half

Under /Over

(29%)5 12(71%)

Under /Over

(53%)9 8(47%)

1.5

2nd Half

Under /Over

(47%)8 9(53%)

/Yes

(59%)10 7(41%)

Both scored
(Yes/No)

No /Yes

(53%)9 8(47%)

GOALS BY TIME PERIOD

Atletico San Luis

Santos Laguna

Shots

Atletico San Luis

Total shots

9.82 avg / game

Blocked

45 total

Avg. 3.21

Santos Laguna

Total shots

7.88 avg / game

Blocked

31 total

Avg. 2.21

Atletico San Luis Pass Santos Laguna

Total passes

5649

Avg. 332 / game

Accurate

81%

Ball possession

49%

Total passes

3566

Avg. 210 / game

Accurate

77%

Ball possession

44%

TOTAL ATTACKS

DANGEROUS ATTACKS

OTHERS

Atletico San Luis

Played games

Santos Laguna

Avg / game Total Total Avg / game

0.18

Clean sheets

0.35

4.00

Corners

2.82

18.71

318

Throw-ins

242

14.24

0.82

Offsides

1.29

2.53

GK saves

3.24

Atletico San Luis

DISCIPLINARY

Santos Laguna

Avg / game Total Total Avg / game

1.82

2.12

0.12

0.35

11.06

188

Fouls

166

9.76

6.65

113

Tackles

120

7.06

NEXT MATCHES

NEXT MATCHES

How We Build the Atletico San Luis vs Santos Laguna Prediction

Betiball.com's prediction for Atletico San Luis vs Santos Laguna on 22 April 2026 is generated by a statistical model that processes over 30 data points per match — including each team's last ten results, expected goals (xG), shots on target, defensive line metrics, set-piece vulnerability, and confirmed squad availability. For this Primera Division de Mexico fixture, our model also factors in home and away performance splits and any confirmed injuries or suspensions reported within 48 hours of kick-off. Every tip includes a probability percentage — not just a pick, but the data behind it.

Atletico San Luis vs Santos Laguna Form Analysis

Heading into this match, both sides carry distinct statistical profiles our model weighs carefully. We assess Atletico San Luis's recent home record, scoring rate, and clean sheet frequency against Santos Laguna's away form — particularly goals conceded on the road and their tendency to score or keep clean sheets in away fixtures. Over/Under 2.5 goals, Both Teams to Score (BTTS), and the Asian Handicap line are all evaluated through this lens before a final recommendation is issued.

Primera Division de Mexico Context: Standings, Form & What's at Stake

League position and match context are decisive inputs. A team fighting relegation defends differently from one chasing European qualification — and our model accounts for that pressure. Check the live Primera Division de Mexico standings and the Primera Division de Mexico form table to understand exactly where Atletico San Luis and Santos Laguna sit and what this result means for both clubs.

Prediction Accuracy & Track Record

Betiball.com publishes a weekly prediction accuracy review so you can verify our historical hit rate across 1x2, Over/Under, and BTTS markets. We do not hide results that went against our tip — full transparency on model performance is a core part of how Betiball.com operates. Our Primera Division de Mexico predictions are among the highest-rated by our users precisely because the data is always shown alongside the recommendation.

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